What is pancreatitis?
The pancreas is a vital organ which lies on the right side of the abdomen.
It has two functions:
1. To produce enzymes which help in digestion of food and,
2. To produce hormones, such as insulin. When the pancreas becomes inflamed,
the disorder is called pancreatitis. It is a disease process that is seen commonly
in the dog. There is no age, sex, or breed predisposition.
There are two main forms of acute (sudden onset) pancreatitis:
1. The mild, edematous form and
2. The more severe, hemorrhagic form. A few dogs that recover from an acute
episode of pancreatitis may continue to have recurrent bouts of the disease,
known as chronic, relapsing pancreatitis. The associated inflammation allows
digestive enzymes to spill into the abdominal cavity; this may result in secondary
damage to surrounding organs, such as the liver, bile ducts, gall bladder, and
What causes it?
The cause of pancreatitis is not known; however, there may be several contributory
factors. It is often associated with a rich, fatty meal. In some cases, it may
be associated with the administration of corticosteroid drugs however, some
dogs with pancreatitis do not have exposure to either.
Under normal conditions, digestive enzymes produced by the pancreas are activated
when they reach the small intestines. In pancreatitis, these enzymes are activated
prematurely in the pancreas instead of in the small intestines. This results
in digestion of the pancreas itself. The clinical signs of pancreatitis are
often variable, and the intensity of the disease will depend on the quantity
of enzymes that are prematurely activated.
What are the clinical signs?
The diagnosis of pancreatitis is based on three criteria: clinical signs,
laboratory tests, and radiographs (x-rays) and/or ultrasound examination. The
disease is typically manifested by nausea, vomiting, fever, abdominal pain,
and diarrhea. If the attack is severe, acute shock, depression, and death may
occur. Laboratory tests usually reveal an elevated white blood cell count; however,
an elevated white blood cell count may also be caused by many other things besides
pancreatitis. The elevation of pancreatic enzymes in the blood is probably the
most helpful criteria in detecting pancreatic disease, but some dogs with pancreatitis
will have normal levels. Radiographs and ultrasound studies may show an area
of inflammation in the location of the pancreas. Unfortunately, many dogs with
pancreatitis will elude detection with any of these tests. Consequently, the
diagnosis of pancreatitis may be tentative in some cases.
How is pancreatitis treated?
The successful management of pancreatitis will depend on early diagnosis and
prompt medical therapy. The mild form of the disease is best treated by resting
the pancreas from its role in digestion. The only way to "turn off" the pancreas
is to withhold all oral fluids and food. This approach is accompanied by intravenous
fluids to maintain normal fluid and electrolyte balance. In addition, anti-inflammatory
drugs are sometimes administered. The presence of shock necessitates the immediate
and intense use of intravenous fluids. Antibiotics are also indicated in many
Will my dog recover?
The prognosis depends on the extent of the disease when presented and a favorable
response to initial therapy. Dogs that present with shock and depression have
a very guarded prognosis. Most of the mild forms of pancreatitis have a good
Will there be any long-term problems?
There are three possible long-term complications that may follow severe or
repeated pancreatitis. If a significant number of cells that produce digestive
enzymes are destroyed, a lack of proper food digestion may follow. This is known
as pancreatic insufficiency and can be treated with daily administration of
enzyme tablets or powder in the food. If a significant number of cells that
produce insulin are destroyed, diabetes mellitus can result and insulin therapy
may be needed. In rare cases, adhesions between the abdominal organs may occur
as a consequence of pancreatitis. However, most dogs recover with no long-term
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